How To Monitor Hormone Therapy for Safety

Hormones are lipids according to the clinical and laboratory research of Emanuel Revici MD. Dr. Revici's research classifies all lipids, and thus all hormones, as either dysoxybiotic or anoxybiotic, later translated as catabolic and anabolic respectively. Simply put, dysoxybiotic or catabolic lipids generate free radicals and in doing so alkalinize tissue. On the other hand, anoxybiotic or anabolic lipids bind oxygen and in doing so acidify tissue.

Dr. Revici devised a laboratory test to determine whether a lipid is catabolic or anabolic. The skin was superficially wounded in a group of mice. At the time of wounding half the mice were injected with the "test" lipid. The other half of the group were not injected. The mice that did not receive an injection were the controls. The pH of the wound (tissue) was measured shortly after the wounding and again in 24 hours.

The pH of the tissue was 7.2 to 7.6 shortly after the wounding on all of the mice.  The "second day crust pH", the tissue pH 24 hours later, remained unchanged on mice without an injection.  All of the injected mice had a wound crust pH higher than 7.6 or lower than 7.2. Mice injected with catabolic lipids had 24 hr wound crusts more alkaline than the controls (pH over 7.6) whereas mice injected with anabolic lipids had 24 hr wound crusts more acid than controls (pH less than 7.2).

According to the second day crust pH, both estrogen and progesterone are anabolic lipids. The Anti-Free Radical Activity on the Health Equations Blood Test Evaluation is an Anabolic Index. An Anabolic Index indirectly measures - again, according the research of Dr. Revici - the amount of anabolic lipid activity in the body. If the Anti-Free Radical Activity is high you do not want to continue to prescribe or take more anabolic lipids, i.e., estrogen and progesterone. However, if prescribing or taking hormones decreases the Anti-Free Radical Activity, or keeps this score low, hormones can be very useful and without the risk.

When there is too much anabolic activity oxygen is bound by the anabolic lipids. Bound oxygen is not available for cell respiration. Cells can no longer  breathe. As a result cells generate lactic acid. Lactic acid acidifies tissues. The consequence of acidification is cell and tissue loss of essential minerals and electrolytes.

According to the second day wound crust pH testosterone is a catabolic lipid. The Free Radical Activity on the Health Equations Blood Test Evaluation is a Catabolic Index. Catabolic lipids generate free radicals. The Catabolic Index measures the amount of catabolic lipid activity in the body. If the Catabolic Index is high you do not want to continue to prescribe or take testosterone.  However, if testosterone decreases the Free Radical Activity, or keeps this score low, testosterone can be very useful both for its hormonal effects and for overall health.

When there is too much catabolic activity oxygen is used to make free radicals. Free radicals damage cells and tissues AND alkalinize the tissues. The consequence of alkalinization is cell and tissue loss of essential  electrolytes and minerals.

When cells loose essential electrolytes and minerals the cells and tissues can no longer function correctly. This is the first step - the pre-clinical or before-you-know-anything-is-going-on step - in the development of symptoms and disease.

The Free Radical and Anti-Free Radical Activity scores in the HEqs BTE can be used to determine whether a person is at risk were s/he to start hormone therapy (synthetic or natural); whether a person is at risk were s/he to continue hormone therapy s/he is currently taking; and, whether a person is at risk taking a botanical, supplement or medication with hormone-like effects.

Both women and men can benefit from different combinations of the many hormones now available - progesterone, the estrogens, testosterone, DHEA, pregnenolone, etc. The benefits extend from menopause and bone density to mind, mood, obesity, cardiovascular disease, cancer and more. Catabolic and anabolic activity can be monitored by the Free Radical and Anti-Free Radical scores in the HEqs BTE. The benefit/risk ratio diminishes for the hormone therapy in proportion to the degree of elevation in either or both of these scores.

 

© Health Equations 2007

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