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TISSUE CHOLESTEROL -- The cholesterol that damages arteries is oxidized tissue and cell LDL cholesterol. Free radicals oxidize cholesterol. Free radicals that damage cholesterol rise in proportion to each of the following: STRESS; lipo-protein(a); homocysteine (via lipo-protein(a)); trans-fatty acids (margarine); lack of anabolic sterols (e.g. cholesterol) and steroids (e.g. progesterone and DHEA); excess copper and iron; radiation exposure; and, inhalation and ingestion (food and water) with chemicals and heavy metals.

The "flame" of free radical activity is fanned by the daunting lack of fresh vegetables in the majority diet. Fresh vegetables are the most (perhaps only) effective source of anti-oxidants. See the work of Dr.'s Weston Price, Melvin Page, Royal Lee and Francis Pottinger at www.ifnh.org.

There is no known relationship between the amount of LDL cholesterol and the amount of oxidized cholesterol. Therefore a patient with high LDL cholesterol can have less oxidized LDL than a patient with low LDL cholesterol.

The Health Equations Database strongly suggests that the Free Radical Activity score is directly proportional to the amount of oxidized LDL cholesterol. The risk of free radical damage and oxidized LDL rises proportionately to Free Radical Activity scores greater than 35.

The Free Radical Activity score is an indirect measure of pro-inflammatory C-20 fatty acids. The Free Radical Activity score is based on the clinical research of Emanuel Revici, MD*.